Our Company

2001

Dr. Janigro

First US patent "Peripheral markers of BBB disruption"

Cleveland Clinic Foundation

2003

Dr. Janigro

Patent "Markers of blood barrier disruption and methods of using same"

Cleveland Clinic Foundation

2004

Publication of "Peripheral markers of blood-brain barrier damage"

270 Pubmed citations

2012

Dr. Janigro

Patent "Serum S100B And Uses Thereof"

Cleveland Clinic Foundation

2018

Drs. Janigro and Diaz-Arrastia

"Biomarkers in traumatic brain injury"

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"The role and diagnostic significance of cellular barriers after concussive head trauma"

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2017

FloTBI

Patent "Assay and Point of Care Device Utilizing Saliva for Diagnosis and Treatment of Neurological Conditions Affecting Brain Health"

2015

Dr. Janigro

Patent "Diagnostic marker for treatment of cerebral ischemia"

Shimojani Inc

FloTBI Inc. founded in Cleveland, OH

2013

Publication of
"Consequences of Repeated
Blood-Brain Barrier
Disruption in Football
Players"

over 270 citations

View
2020

Bazarian publishes "S100B outperforms clinical decision rules for the identification of intracranial injury on head CT scan after mild traumatic brain injury"

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Publication of "Is Salivary S100B a Biomarker of Traumatic Brain Injury? A Pilot Study"

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Aceti et al. "Serum S100B protein as a marker of severity in Covid-19 patients"

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2021

"Serum S-100β as a possible marker of blood–brain barrier disruption"

Reaches over 330 citations

"Peripheral Blood and Salivary Biomarkers of Blood-Brain Barrier Permeability and Neuronal Damage: Clinical and Applied Concepts"

Published in Frontiers

View
2001

Dr. Janigro

First US patent "Peripheral markers of BBB disruption"

Cleveland Clinic Foundation

2003

Dr. Janigro

Patent "Markers of blood barrier disruption and methods of using same"

Cleveland Clinic Foundation

2004

Publication of "Peripheral markers of blood-brain barrier damage"

270 Pubmed citations

2012

Dr. Janigro

Patent "Serum S100B And Uses Thereof"

Cleveland Clinic Foundation

2013

Publication of
"Consequences of Repeated
Blood-Brain Barrier
Disruption in Football
Players"

over 270 citations

View
2015

Dr. Janigro

Patent "Diagnostic marker for treatment of cerebral ischemia"

Shimojani Inc

FloTBI Inc. founded in Cleveland, OH

2017

FloTBI

Patent "Assay and Point of Care Device Utilizing Saliva for Diagnosis and Treatment of Neurological Conditions Affecting Brain Health"

2018

Drs. Janigro and Diaz-Arrastia

"Biomarkers in traumatic brain injury"

View

"The role and diagnostic significance of cellular barriers after concussive head trauma"

View
2020

Bazarian publishes "S100B outperforms clinical decision rules for the identification of intracranial injury on head CT scan after mild traumatic brain injury"

View

Publication of "Is Salivary S100B a Biomarker of Traumatic Brain Injury? A Pilot Study"

View

Aceti et al. "Serum S100B protein as a marker of severity in Covid-19 patients"

View
2021

"Serum S-100β as a possible marker of blood–brain barrier disruption"

Reaches over 330 citations

"Peripheral Blood and Salivary Biomarkers of Blood-Brain Barrier Permeability and Neuronal Damage: Clinical and Applied Concepts"

Published in Frontiers

View

Testimonials

Ramon
Diaz-Arrastia MD, PhD

"Saliva is a very promising biological fluid in which to look for TBI biomarkers. It is likely to be at least as good as blood."

Olli Tenovuo MD, PhD

"Measuring brain biomarkers in saliva instead of blood would improve current standards of TBI triage, in particular with the FloTBI device."

Articles

Brain Injuries Are Common in Battle. The Military Has No Reliable Test for Them.

Cleveland Clinic using blood samples from Baldwin-Wallace football players for concussion study

Video

D - Concussion Blood Test Measures Head Injury

Cleveland Clinic researcher, Damir Janigro, PhD, discusses a test to discover silent concussions through a blood test. Concussions can be rated through this test and gives parents, coaches and trainers information to keep players healthy and safe.

Watch video

Teams & Key Roles

damir anigro
Damir Janigro, PhD FAES

CEO and CSO, Founder Principal Investigator Scientist and Inventor of the FloTBI Technology

robert schmidt
Robert Schmidt, MBA, JD, PE

Professional Engineer, 50 years of military contracting and commercialization experience

matthew mahoney
Matthew Mahoney, CPA CFO
nora mahoney
Nora Mahoney

Investment Consultant Investor

brooke hradisky
Brooke Hradisky

Investment Consultant Investor

chris mckenna
Chris McKenna

Commercialization Expert Carlton McKenna Investor

Advisory Board

Ramon Diaz-Arrastia MD
Ramon Diaz-Arrastia MD

Clinical Advisor, Presidential Professor of Neurology, Penn Presbyterian Medical Center

Gerry Grant MD
Gerry Grant MD

Clinical Advisor, Stanford Pediatric Neurosurgeon, former LTC USAF, Iraq theater hospital chief of Neurosurgery.

Francesca Bisulli
Francesca Bisulli, MD PhD

University of Bologna
Italy
Clinical
advisor-Neurology

nNicola Marchi, PhD
Nicola Marchi, PhD

CNRC
Montpellier, France Scientific Advisor

Tiziana Granata, MD
Tiziana Granata, MD

Besta Institute
Milano,
Italy
Clinical Advisor-Neurology